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PGLYRP4 Antibody

  • 货号：
    CSB-PA017865LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA017865LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA017865LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PGLYRP4 Polyclonal antibody
  • Uniprot No.：
    Q96LB8
  • 基因名：
    PGLYRP4
  • 别名：
    Peptidoglycan recognition protein 4 antibody; Peptidoglycan recognition protein I-beta antibody; Peptidoglycan recognition protein intermediate beta antibody; Pglyrp4 antibody; PGLYRPIbeta antibody; PGRP-I-beta antibody; PGRP4_HUMAN antibody; PGRPIB antibody; SBBI67 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Peptidoglycan recognition protein 4 protein (18-317AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，PGLYRP4 Antibody (CSB-PA017865LA01HU)，的标记方式是Non-conjugated。对于PGLYRP4 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA017865LB01HU PGLYRP4 Antibody, HRP conjugated ELISA
    FITC CSB-PA017865LC01HU PGLYRP4 Antibody, FITC conjugated
    Biotin CSB-PA017865LD01HU PGLYRP4 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.
  • 基因功能参考文献：
    1. a significant induction of three PGLYRPs 2-4 in primary human corneal epithelial cells (HCECs) exposed to live or heat-killed Candida albicans, is reported. PMID: 26039076
    2. This study demonistrated that PGLYRP4 single-nucleotide polymorphisms is risk of Parkinson's disease. PMID: 24838182
    3. Results describe the function of mammalian antimicrobial peptidoglycan recognition proteins 3 and 4, and show that they are a new class of bactericidal and bacteriostatic proteins. PMID: 16354652
    4. Data are consistent with previous reports of association of psoriasis with genes on 1q21, and suggest a role for Pglyrp4 in skin biology. PMID: 16362825
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    N-acetylmuramoyl-L-alanine amidase 2 family
  • 组织特异性：
    Detected in skin epidermis, eccrine sweat glands and ducts, mucous cells in the submandibular salivary gland, mucous cells in the throat, ciliary body epithelial cells of the eye, small intestine, colon, stomach and in mature epithelial cells of the tongu
  • 数据库链接：

    HGNC: 30015

    OMIM: 608198

    KEGG: hsa:57115

    STRING: 9606.ENSP00000352672

    UniGene: Hs.58356