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PGPEP1 Antibody

  • 货号：
    CSB-PA017874GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9NXJ5
  • 基因名：
    PGPEP1
  • 别名：
    2810003H13Rik antibody; 5 oxoprolyl peptidase antibody; 5-oxoprolyl-peptidase antibody; FLJ20208 antibody; MGC10812 antibody; PAP I antibody; PAP-I antibody; PAPI antibody; Pcp antibody; PGI antibody; pGlu peptidase I antibody; PGP antibody; PGP I antibody; PGP-I antibody; Pgpep1 antibody; PGPI antibody; PGPI_HUMAN antibody; Pyroglutamyl aminopeptidase I antibody; Pyroglutamyl peptidase 1 antibody; pyroglutamyl peptidase I antibody; Pyroglutamyl-peptidase 1 antibody; Pyroglutamyl-peptidase I antibody; pyrrolidone carboxylate peptidase antibody; Pyrrolidone-carboxylate peptidase antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human PGPEP1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
  • 基因功能参考文献：
    1. cytosolic peptidases(puromycin-sensitive aminopeptidase (PSA), aminopeptidase B (APB) and pyroglutamyl-peptidase I (PGI) ) may be involved in colorectal carcinogenesis PMID: 26078706
    2. The specific reduction of the levels of pyroglutamyl-aminopeptidase activity in serum of liver cirrhosis patients might be considered as a potential candidate to be included in a combination of markers for the diagnosis of this disease. PMID: 25687677
    3. cloning and sequencing of the human (AJ278828) pyroglutamyl-peptidase I PMID: 12651114
    4. VX-710 modulates Pgp, MRP-1, and BCRP(R482), and has potential as a clinical broad-spectrum multidrug resistance modulator in malignancies. PMID: 15014037
    5. The activities of pyroglutamyl peptidase I and prolyl endopeptidase in necrozoospermia were found to be higher in the corresponding soluble and particulate sperm fractions, respectively, with respect to those measured in normozoospermic semen PMID: 15380924

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  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Peptidase C15 family
  • 数据库链接：

    HGNC: 13568

    OMIM: 610694

    KEGG: hsa:54858

    STRING: 9606.ENSP00000269919

    UniGene: Hs.131776