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PHKB Antibody

  • 货号：
    CSB-PA849977ESR2HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA849977ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA849977ESR2HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PHKB Polyclonal antibody
  • Uniprot No.：
    Q93100
  • 基因名：
  • 别名：
    DKFZp781E15103 antibody; FLJ41698 antibody; KPBB_HUMAN antibody; PHKB antibody; Phosphorylase b kinase regulatory subunit beta antibody; Phosphorylase kinase B antibody; Phosphorylase kinase beta polypeptide antibody; Phosphorylase kinase beta subunit antibody; Phosphorylase kinase subunit beta antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Phosphorylase b kinase regulatory subunit beta protein (854-1093AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation.
  • 基因功能参考文献：
    1. PHKb affects colorectal cancer cell growth and represents a novel prognostic biomarker. PMID: 28275865
    2. Analysis showed that the glycogen phosphorylase kinase beta-subunit (PHKB) interacted with the C-terminal region of KIAA1199 protein. PMID: 25051373
  • 相关疾病：
    Glycogen storage disease 9B (GSD9B)
  • 亚细胞定位：
    Cell membrane; Lipid-anchor; Cytoplasmic side.
  • 蛋白家族：
    Phosphorylase b kinase regulatory chain family
  • 数据库链接：

    HGNC: 8927

    OMIM: 172490

    KEGG: hsa:5257

    STRING: 9606.ENSP00000313504

    UniGene: Hs.78060