Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. PIGL Antibody

PIGL Antibody

  • 货号：
    CSB-PA897465LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA897465LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA897465LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PIGL Polyclonal antibody
  • Uniprot No.：
    Q9Y2B2
  • 基因名：
    PIGL
  • 别名：
    N acetylglucosaminylphosphatidylinositol deacetylase antibody; N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase antibody; Phosphatidylinositol glycan anchor biosynthesis class L antibody; Phosphatidylinositol glycan class L antibody; Phosphatidylinositol-glycan biosynthesis class L protein antibody; PIG-L antibody; Pigl antibody; PIGL_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase protein (23-252AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，PIGL Antibody (CSB-PA897465LA01HU)，的标记方式是Non-conjugated。对于PIGL Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA897465LB01HU PIGL Antibody, HRP conjugated ELISA
    FITC CSB-PA897465LC01HU PIGL Antibody, FITC conjugated
    Biotin CSB-PA897465LD01HU PIGL Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.
  • 基因功能参考文献：
    1. c.336-2A>G variant in PIGL associated with developmental disorder resulted in exon skipping. PMID: 28327575
    2. these findings indicate that patients with a clinical diagnosis of CHIME syndrome and a single identifiable mutation in PIGL warrant further investigation for copynumber changes involving PMID: 28371479
    3. fd hrhr rt eruj jej PMID: 25706356
    4. Whole-exome sequencing on five previously reported CHIME cases identified PIGL (N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase) as required for glycosylphosphatidylinositol anchor formation. PMID: 22444671
  • 相关疾病：
    Coloboma, congenital heart disease, ichthyosiform dermatosis, mental retardation and ear anomalies syndrome (CHIME)
  • 亚细胞定位：
    Endoplasmic reticulum membrane; Single-pass membrane protein.
  • 蛋白家族：
    PIGL family
  • 数据库链接：

    HGNC: 8966

    OMIM: 280000

    KEGG: hsa:9487

    STRING: 9606.ENSP00000225609

    UniGene: Hs.499793