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PIGR Antibody

  • 货号：
    CSB-PA017981LA01BO
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: Polymeric immunoglobulin receptor antibody at 2μg/ml + HL60 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 83, 59 kDa
      Observed band size: 83 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Bovine PIGR Polyclonal antibody
  • Uniprot No.：
    P81265
  • 基因名：
    PIGR
  • 别名：
    PIGR antibody; Polymeric immunoglobulin receptor antibody; PIgR antibody; Poly-Ig receptor) [Cleaved into: Secretory component] antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Bovine
  • 免疫原：
    Recombinant Bovine Polymeric immunoglobulin receptor protein (399-599AA)
  • 免疫原种属：
    Bovine
  • 标记方式：
    Non-conjugated

    本页面中的产品，PIGR Antibody (CSB-PA017981LA01BO)，的标记方式是Non-conjugated。对于PIGR Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA017981LB01BO PIGR Antibody, HRP conjugated ELISA
    FITC CSB-PA017981LC01BO PIGR Antibody, FITC conjugated
    Biotin CSB-PA017981LD01BO PIGR Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Mediates selective transcytosis of polymeric IgA and IgM across mucosal epithelial cells. Binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.; Through its N-linked glycans ensures anchoring of secretory IgA (sIgA) molecules to mucus lining the epithelial surface to neutralize extracellular pathogens. On its own (free form) may act as a non-specific microbial scavenger to prevent pathogen interaction with epithelial cells.
  • 基因功能参考文献：
    1. This study evaluated the production of polymeric immunoglobulin receptor and immunoglobulin A in the salivary glands of cattle. PMID: 23395346
  • 亚细胞定位：
    [Polymeric immunoglobulin receptor]: Cell membrane; Single-pass type I membrane protein.; [Secretory component]: Secreted.
  • 组织特异性：
    Found in mammary gland, jejunum, lung, kidney and small intestine.
  • 数据库链接：

    KEGG: bta:281401

    STRING: 9913.ENSBTAP00000026377

    UniGene: Bt.4695