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PIK3C2G Antibody

  • 货号：
    CSB-PA782930
  • 规格：
    ￥880
  • 图片：
    • Western blot analysis of A549 using PI 3-Kinase C2γ antibody.. Secondary antibody was diluted at 1:20000
  • 其他：

产品详情

  • Uniprot No.：
    O75747
  • 基因名：
  • 别名：
    PIK3C2G antibody; Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma antibody; PI3K-C2-gamma antibody; PtdIns-3-kinase C2 subunit gamma antibody; EC 2.7.1.154 antibody; Phosphoinositide 3-kinase-C2-gamma antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human PI 3-Kinase C2γ.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Generates phosphatidylinositol 3-phosphate (PtdIns3P) and phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) that act as second messengers. May play a role in SDF1A-stimulated chemotaxis.
  • 基因功能参考文献：
    1. Data indicate substituents of benzensulfonamide and pyrazine as phosphoinositide 3-kinase-C2gamma (PI3K-C2GAMMA) inhibitors. PMID: 24983663
    2. The associations of five SNPs (SNPs1-5: A-5468G, A-3333G, C-1794T, C437T and T9148C) of the class II phosphoinositide 3-kinase gamma-subunit (PIK3C2G) gene with type 2 diabetes were examined. PMID: 17991425
  • 亚细胞定位：
    Membrane; Peripheral membrane protein.
  • 蛋白家族：
    PI3/PI4-kinase family
  • 组织特异性：
    Highly expressed in liver, prostate and testis. Lower levels in small intestine, kidney and pancreas.
  • 数据库链接：

    HGNC: 8973

    OMIM: 609001

    KEGG: hsa:5288

    STRING: 9606.ENSP00000266497

    UniGene: Hs.22500