PLA1A Antibody
产品详情
-
产品名称:Rabbit anti-Homo sapiens (Human) PLA1A Polyclonal antibody
-
Uniprot No.:Q53H76
-
基因名:
-
别名:AA986889 antibody; NMD antibody; OTTHUMP00000215248 antibody; OTTHUMP00000215249 antibody; OTTHUMP00000215250 antibody; Phosphatidylserine specific phospholipase A1 antibody; Phosphatidylserine specific phospholipase A1alpha antibody; Phosphatidylserine-specific phospholipase A1 antibody; Phospholipase A1 member A antibody; pla1a antibody; PLA1A_HUMAN antibody; PS PLA1 antibody; PS-PLA1 antibody; PSPLA 1 antibody; PSPLA1 antibody
-
宿主:Rabbit
-
反应种属:Human
-
免疫原:Recombinant Human Phospholipase A1 member A protein (293-398AA)
-
免疫原种属:Homo sapiens (Human)
-
标记方式:Non-conjugated
本页面中的产品,PLA1A Antibody (CSB-PA018084LA01HU),的标记方式是Non-conjugated。对于PLA1A Antibody,我们还提供其他标记。见下表:
-
克隆类型:Polyclonal
-
抗体亚型:IgG
-
纯化方式:>95%, Protein G purified
-
浓度:It differs from different batches. Please contact us to confirm it.
-
保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
产品提供形式:Liquid
-
应用范围:ELISA, WB, IHC
-
推荐稀释比:
Application Recommended Dilution WB 1:500-1:5000 IHC 1:200-1:500 -
Protocols:
-
储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相关产品
靶点详情
-
功能:Hydrolyzes the ester bond of the acyl group attached at the sn-1 position of phosphatidylserines (phospholipase A1 activity) and 1-acyl-2-lysophosphatidylserines (lysophospholipase activity) in the pathway of phosphatidylserines acyl chain remodeling. Cleaves phosphatidylserines exposed on the outer leaflet of the plasma membrane of apoptotic cells producing 2-acyl-1-lysophosphatidylserines, which in turn enhance mast cell activation and histamine production. Has no activity toward other glycerophospholipids including phosphatidylcholines, phosphatidylethanolamines, phosphatidic a...显示更多
-
基因功能参考文献:
- Serum PS-PLA1 levels were significantly higher in the melanoma subjects and associated with the clinical stages. PMID: 29500864
- the LysoPA levels might be determined largely by LysoPC and LysoPI (possible precursors) and the PS-PLA1-mediated pathway might be involved in the production of LysoPS in gastric cancer. PMID: 28143894
- PS-PLA1 expression in colorectal cancer is associated with tumor invasion and metastasis. PMID: 25750298
- These data suggest that PLA1A plays an important role in bridging the membrane-associated NS2-E2 complex and the NS5A-associated replication complex via its interaction with hepatitis C virus E2, NS2, and NS5A. PMID: 25505071
- PLA1A2 polymorphism is associated with mortality in participants whose hemoglobin A1c ranges from 5.5% to 6.5%. PMID: 24886443
- Overall, our study shed the light on new structural features of the phospholipase activity of pancreatic lipase family members. PMID: 24368210
- These results suggest that the expression of PS-PLA(1) mRNA in THP-1-derived macrophages is activated via TLR4. PMID: 20573295
- polymorphisms in the gene encoding phosphatidylserine-specific phospholipase A1 PMID: 12436198
收起更多
-
亚细胞定位:Secreted.
-
蛋白家族:AB hydrolase superfamily, Lipase family
-
组织特异性:Widely expressed. Expressed in placenta, prostate and liver. Weakly or not expressed in skin, leukocytes, platelets, colon, spleen, lung, muscle and kidney.
-
数据库链接:
HGNC: 17661
OMIM: 607460
KEGG: hsa:51365
STRING: 9606.ENSP00000273371
UniGene: Hs.437451