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PLPBP Antibody

  • 货号：
    CSB-PA018755LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA018755LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA018755LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PLPBP Polyclonal antibody
  • Uniprot No.：
    O94903
  • 基因名：
    PLPBP
  • 别名：
    FLJ11861 antibody; Proline synthase co-transcribed bacterial homolog protein antibody; Proline synthetase co transcribed bacterial homolog antibody; Proline synthetase co transcribed homolog (bacterial) antibody; PROSC antibody; PROSC_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Pyridoxal phosphate homeostasis protein (1-275AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，PLPBP Antibody (CSB-PA018755LA01HU)，的标记方式是Non-conjugated。对于PLPBP Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA018755LB01HU PLPBP Antibody, HRP conjugated ELISA
    FITC CSB-PA018755LC01HU PLPBP Antibody, FITC conjugated
    Biotin CSB-PA018755LD01HU PLPBP Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.
  • 基因功能参考文献：
    1. We therefore confirm PROSC as a novel gene for vitamin-B6-dependent epilepsy and delineate a non-specific plasma vitamin B6 profile under pyridoxine treatment. PMID: 28391250
    2. Exploiting the universality of the Synechococcus elongatus COG0325 (PiPY) functions, it has been used in site-directed mutagenesis studies to shed light on disease causation by epilepsy-associated mutations in the human COG0325 gene PROSC. PMID: 28914444
    3. studies suggest that PROSC is involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate, supplying this cofactor to apoenzymes while minimizing any toxic side reactions PMID: 27912044
  • 相关疾病：
    Epilepsy, early-onset, vitamin B6-dependent (EPVB6D)
  • 蛋白家族：
    Pyridoxal phosphate-binding protein YggS/PROSC family
  • 组织特异性：
    Ubiquitous.
  • 数据库链接：

    HGNC: 9457

    OMIM: 604436

    KEGG: hsa:11212

    STRING: 9606.ENSP00000333551

    UniGene: Hs.304792