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PMPCA Antibody

  • 货号：
    CSB-PA606021ESR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA606021ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA606021ESR1HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PMPCA Polyclonal antibody
  • Uniprot No.：
    Q10713
  • 基因名：
  • 别名：
    1200002L24Rik antibody; 4933435E07Rik antibody; Alpha MPP antibody; Alpha-MPP antibody; FLJ26258 antibody; Inositol polyphosphate 5 phosphatase, 72 kD antibody; INPP5E antibody; KIAA0123 antibody; MGC104197 antibody; MGC93916 antibody; Mitochondrial matrix processing protease, alpha subunit antibody; mitochondrial processing peptidase subunit alpha antibody; Mitochondrial-processing peptidase subunit alpha antibody; MPPA_HUMAN antibody; P 55 antibody; P-55 antibody; Peptidase (mitochondrial processing) alpha antibody; pmpca antibody; RP11-413M3.1 antibody; RP23-306D20.8 antibody; SCAR2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Mitochondrial-processing peptidase subunit alpha protein (456-525AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.
  • 基因功能参考文献：
    1. study represents the first time that defects in PMPCA and mitochondrial processing peptidase have been described in association with a disease phenotype in humans. PMID: 25808372
    2. OxLDL triggers retrograde translocation of arginase2 in aortic endothelial cells via ROCK and mitochondrial processing peptidase. PMID: 24903103
  • 相关疾病：
    Spinocerebellar ataxia, autosomal recessive, 2 (SCAR2)
  • 亚细胞定位：
    Mitochondrion matrix. Mitochondrion inner membrane.
  • 蛋白家族：
    Peptidase M16 family
  • 组织特异性：
    Ubiquitously expressed with highest expression in fetal tissues and adult brain, cerebellum and cerebellar vermis.
  • 数据库链接：

    HGNC: 18667

    OMIM: 213200

    KEGG: hsa:23203

    STRING: 9606.ENSP00000360782

    UniGene: Hs.495471