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PNRC1 Antibody

  • 货号：
    CSB-PA018289GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q12796
  • 基因名：
  • 别名：
    PNRC1 antibody; PROL2 antibody; Proline-rich nuclear receptor coactivator 1 antibody; Proline-rich protein 2 antibody; Protein B4-2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Human PNRC1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Nuclear receptor coactivator. May play a role in signal transduction.
  • 基因功能参考文献：
    1. PNRC and Grb2, by interacting with each other, can suppress nuclear receptor-mediated regulation and growth factor-mediated regulation in human breast tissue PMID: 15122321
    2. Functional analysis of the 5' flanking region of the human PNRC gene by deletion mutagenesis, transient transfection and luciferase assays revealed that the -123/+27 region is the minimal promoter of the human PNRC gene. PMID: 18281297
    3. Three human PNRC splicing variants designated PNRC1c, PNRC1d and PNRC1f, are identified. PMID: 18703122
    4. RFX1 specifically bind to promoter region and negatively regulate the transcription of the human PNRC gene. PMID: 19334528
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    PNRC family, PNRC1 subfamily
  • 组织特异性：
    Expressed in liver, lung, fat and NK/T cells.
  • 数据库链接：

    HGNC: 17278

    OMIM: 606714

    KEGG: hsa:10957

    STRING: 9606.ENSP00000336931

    UniGene: Hs.75969