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PODN Antibody

  • 货号：
    CSB-PA007057
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q7Z5L7
  • 基因名：
    PODN
  • 别名：
    9430070G18 antibody; LRRGT00160 antibody; MGC24995 antibody; PCAN antibody; Podn antibody; PODN_HUMAN antibody; Podocan antibody; Podocan proteoglycan antibody; RP23 40G2.7 antibody; SLRR5A antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human Podocan.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Negatively regulates cell proliferation and cell migration.
  • 基因功能参考文献：
    1. It was apparent that HP upregulates miR-3180-5p, which inhibits the expression of PODN and promotes HBSMC proliferation via the cdk2 signaling pathway. PMID: 27608612
    2. Podocan appears to be a potent negative regulator of the migration and proliferation of vascular smooth muscle cells. PMID: 24043300
    3. PODN was characterized in cultured cells. PMID: 15063725
  • 亚细胞定位：
    [Isoform 1]: Secreted, extracellular space, extracellular matrix.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Cytoplasm.; [Isoform 4]: Cytoplasm.
  • 蛋白家族：
    Small leucine-rich proteoglycan (SLRP) family, SLRP class V subfamily
  • 组织特异性：
    Kidney, heart, liver, pancreas and vascular smooth muscle cells. Also detected in aortic intima (at protein level).
  • 数据库链接：

    HGNC: 23174

    OMIM: 608661

    KEGG: hsa:127435

    STRING: 9606.ENSP00000308315

    UniGene: Hs.586141