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POLR2J Antibody

  • 货号：
    CSB-PA030120
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    P52435
  • 基因名：
    POLR2J
  • 别名：
    DNA directed RNA polymerase II subunit RPB11 a antibody; DNA-directed RNA polymerase II 13.3 kDa polypeptide antibody; DNA-directed RNA polymerase II 13.3 kDa polypeptide antibody; DNA-directed RNA polymerase II subunit J 1 antibody; DNA-directed RNA polymerase II subunit J-1 antibody; DNA-directed RNA polymerase II subunit RPB11-a antibody; hRPB 14 antibody; hRPB14 antibody; POLR 2J1 antibody; POLR2J antibody; POLR2J1 antibody; polymerase (RNA) II (DNA directed) polypeptide J 13.3kDa antibody; polymerase (RNA) II (DNA directed) polypeptide J 13.3kDa antibody; RNA polymerase II 13.3 kDa subunit antibody; RNA polymerase II subunit B11 a antibody; RNA polymerase II subunit B11-a antibody; RPB 11 antibody; RPB 11A antibody; RPB 11m antibody; RPB11 antibody; RPB11_HUMAN antibody; RPB11a antibody; RPB11m antibody; Rpo2-4 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human POLR2J1.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.
  • 基因功能参考文献：
    1. POLR2J interacts with three different subunits of eIF3, eIF3a, eIF3i, and eIF3m. PMID: 22022972
    2. Four independent genes(POLR2J1, POLR2J2, POLR2J3, POLR2J4) encoding various variants of the hRPB11 subunit of Homo sapiens RNA polymerase II were revealed in human chromosome 7 PMID: 15586814
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family
  • 组织特异性：
    Ubiquitously expressed. High expression was found in heart and skeletal muscle.
  • 数据库链接：

    HGNC: 9197

    OMIM: 604150

    KEGG: hsa:5439

    STRING: 9606.ENSP00000292614

    UniGene: Hs.654952