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POLR3E Antibody

  • 货号：
    CSB-PA868333LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA868333LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA868333LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) POLR3E Polyclonal antibody
  • Uniprot No.：
    Q9NVU0
  • 基因名：
    POLR3E
  • 别名：
    POLR3E antibody; KIAA1452 antibody; DNA-directed RNA polymerase III subunit RPC5 antibody; RNA polymerase III subunit C5 antibody; DNA-directed RNA polymerase III 80 kDa polypeptide antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human DNA-directed RNA polymerase III subunit RPC5 protein (1-260AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，POLR3E Antibody (CSB-PA868333LA01HU)，的标记方式是Non-conjugated。对于POLR3E Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA868333LB01HU POLR3E Antibody, HRP conjugated ELISA
    FITC CSB-PA868333LC01HU POLR3E Antibody, FITC conjugated
    Biotin CSB-PA868333LD01HU POLR3E Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.
  • 亚细胞定位：
    Nucleus.
  • 数据库链接：

    HGNC: 30347

    OMIM: 617815

    KEGG: hsa:101060521

    STRING: 9606.ENSP00000299853

    UniGene: Hs.460298