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POLR3F Antibody

  • 货号：
    CSB-PA018348GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9H1D9
  • 基因名：
    POLR3F
  • 别名：
    DNA directed RNA polymerase III 39 kDa polypeptide antibody; DNA directed RNA polymerase III 39 kDa polypeptide F antibody; DNA directed RNA polymerase III subunit F antibody; DNA directed RNA polymerase III subunit RPC6 antibody; DNA directed RNA polymerases III 39 kDa polypeptide antibody; DNA-directed RNA polymerase III subunit F antibody; DNA-directed RNA polymerase III subunit RPC6 antibody; MGC13517 antibody; Polr3f antibody; Polymerase (RNA) III (DNA directed) polypeptide F antibody; RNA polymerase III 39 kDa subunit antibody; RNA polymerase III C39 subunit antibody; RNA polymerase III subunit C6 antibody; RPC 39 antibody; RPC 6 antibody; RPC39 antibody; RPC6 antibody; RPC6_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human POLR3F
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct RNA Pol III binding to the TFIIIB-DNA complex. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway. Preferentially binds double-stranded DNA (dsDNA).
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Eukaryotic RPC34/RPC39 RNA polymerase subunit family
  • 数据库链接：

    HGNC: 15763

    OMIM: 617455

    KEGG: hsa:10621

    STRING: 9606.ENSP00000366828

    UniGene: Hs.472227