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PPFIBP2 Antibody

  • 货号：
    CSB-PA847688LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: PPFIBP2 antibody at 6μg/ml + HepG2 whole cell lysate
      Secondary
      Goat polyclonal to rabbit at 1/10000 dilution
      Predicted band size: 99, 87, 84 kDa
      Observed band size: 99 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PPFIBP2 Polyclonal antibody
  • Uniprot No.：
    Q8ND30
  • 基因名：
    PPFIBP2
  • 别名：
    PPFIBP2 antibody; Liprin-beta-2 antibody; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2 antibody; PTPRF-interacting protein-binding protein 2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Liprin-beta-2 protein (101-400AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，PPFIBP2 Antibody (CSB-PA847688LA01HU)，的标记方式是Non-conjugated。对于PPFIBP2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA847688LB01HU PPFIBP2 Antibody, HRP conjugated ELISA
    FITC CSB-PA847688LC01HU PPFIBP2 Antibody, FITC conjugated
    Biotin CSB-PA847688LD01HU PPFIBP2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A.
  • 基因功能参考文献：
    1. Analysis of the role of liprin-beta1 and liprin-beta2 has shown that while liprin-beta1 contributes positively to tumour cell motility in vitro; liprin-beta2 has a negative effect on both cell motility and invasion. PMID: 26663347
    2. rs12791447 is associated with prostate cancer susceptibility in Asians. mRNA levels of PPFIBP2 are differentially expressed in prostate tumours and paired normal tissues. PMID: 26443449
    3. Knockdown of either Rab17 or liprin-beta2 restores invasiveness of ERK2-depleted cells, indicating that ERK2 drives invasion of MDA-MB-231 cells by suppressing expression of these genes. PMID: 22328529
    4. analysis of crystal structure of the central coiled-coil domain from human liprin-beta2 PMID: 21462929
  • 蛋白家族：
    Liprin family, Liprin-beta subfamily
  • 组织特异性：
    Widely expressed.
  • 数据库链接：

    HGNC: 9250

    OMIM: 603142

    KEGG: hsa:8495

    STRING: 9606.ENSP00000299492

    UniGene: Hs.655714