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PPIL2 Antibody

  • 货号：
    CSB-PA621661ESR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA621661ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA621661ESR1HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PPIL2 Polyclonal antibody
  • Uniprot No.：
    Q13356
  • 基因名：
  • 别名：
    ntibody; CYC4 antibody; Cyclophilin 60 antibody; Cyclophilin 60kDa antibody; Cyclophilin like protein Cyp 60 antibody; Cyclophilin-60 antibody; Cyclophilin-like protein Cyp-60 antibody; CYP60 antibody; hCyP 60 antibody; MGC33174 antibody; MGC787 antibody; Peptidyl prolyl cis trans isomerase like 2 antibody; Peptidyl-prolyl cis-trans isomerase-like 2 antibody; Peptidylprolyl cis trans isomerase antibody; Peptidylprolyl isomerase cyclophilin like 2 antibody; PPIase antibody; PPIL2 antibody; PPIL2_HUMAN antibody; Rotamase antibody; Rotamase PPIL2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Peptidyl-prolyl cis-trans isomerase-like 2 protein (1-260AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Has a ubiquitin-protein ligase activity acting as an E3 ubiquitin protein ligase or as an ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates. By mediating 'Lys-48'-linked polyubiquitination of proteins could target them for proteasomal degradation. May also function as a chaperone, playing a role in transport to the cell membrane of BSG/Basigin for instance. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity.
  • 基因功能参考文献：
    1. cyclophilin 60 regulates cell surface expression of CD147/EMMPRIN PMID: 15946952
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Cyclophilin-type PPIase family, PPIL2 subfamily
  • 组织特异性：
    Highest expression in thymus, pancreas and testis. Also detected in heart, placenta, lung, liver, skeletal muscle, kidney, spleen, prostate, ovary, small intestine and colon. Poorly detected in brain and leukocytes. Strong protein expression in lymph node
  • 数据库链接：

    HGNC: 9261

    OMIM: 607588

    KEGG: hsa:23759

    STRING: 9606.ENSP00000390427

    UniGene: Hs.438587