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PPP1R12B Antibody

  • 货号：
    CSB-PA018512GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    O60237
  • 基因名：
  • 别名：
    PPP1R12B antibody; MYPT2 antibody; Protein phosphatase 1 regulatory subunit 12B antibody; Myosin phosphatase-targeting subunit 2 antibody; Myosin phosphatase target subunit 2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human PPP1R12B
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Regulates myosin phosphatase activity. Augments Ca(2+) sensitivity of the contractile apparatus.
  • 基因功能参考文献：
    1. PPP1R12B is associated with childhood asthma in a Russian population. PMID: 23640410
    2. Results describe the characterization and function of MYPT2, a target subunit of myosin phosphatase in heart. PMID: 16431080
    3. analysis of the interaction between the coiled coil leucine zipper of cGMP-dependent protein kinase Ialpha and the C terminus of the myosin binding subunit of the myosin light chain phosphatase PMID: 18782776
  • 亚细胞定位：
    Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber.
  • 组织特异性：
    Detected in skeletal muscle, fetal and adult heart, brain, placenta, kidney, spleen, thymus, pancreas and lung. Isoform 3 and isoform 4 are heart specific.
  • 数据库链接：

    HGNC: 7619

    OMIM: 603768

    KEGG: hsa:4660

    STRING: 9606.ENSP00000384496

    UniGene: Hs.444403