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PPP1R14D Antibody

  • 货号：
    CSB-PA003840
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of COLO205 cells using PPP1R14D Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q9NXH3
  • 基因名：
    PPP1R14D
  • 别名：
    PPP1R14D antibody; GBPI antibody; Protein phosphatase 1 regulatory subunit 14D antibody; Gastrointestinal and brain-specific PP1-inhibitory protein 1 antibody; GBPI-1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human PPP1R14D.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Inhibitor of PPP1CA. Has inhibitory activity only when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.
  • 基因功能参考文献：
    1. A gastrointestinal- and brain-specific PP1 inhibitory protein (GBPI-1)is activated by PKC phosphorylation. A longer GBPI-2 splice variant mRNA is found in testes. PMID: 12974676
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    PP1 inhibitor family
  • 组织特异性：
    Detected in colon, intestine, kidney and brain cortex.
  • 数据库链接：

    HGNC: 14953

    OMIM: 613256

    KEGG: hsa:54866

    STRING: 9606.ENSP00000398342

    UniGene: Hs.192927