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PPP1R9A Antibody

  • 货号：
    CSB-PA018557GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9ULJ8
  • 基因名：
    PPP1R9A
  • 别名：
    FLJ20068 antibody; KIAA1222 antibody; NEB1_HUMAN antibody; Neurabin I antibody; Neurabin-1 antibody; Neurabin-I antibody; Neurabin1 antibody; NeurabinI antibody; Neural tissue specific F actin binding protein I antibody; Neural tissue-specific F-actin-binding protein I antibody; NRB 1 antibody; NRB I antibody; NRB1 antibody; NRBI antibody; Ppp1r9a antibody; Protein phosphatase 1 regulatory (inhibitor) subunit 9A antibody; Protein phosphatase 1 regulatory subunit 9A antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human PPP1R9A
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Binds to actin filaments (F-actin) and shows cross-linking activity. Binds along the sides of the F-actin. May be involved in neurite formation. Inhibits protein phosphatase 1-alpha activity.
  • 基因功能参考文献：
    1. MARCKS and PPP1R9A might contribute to spine loss in schizophrenia and bipolar disorder through their interactions. PMID: 25757715
    2. CHN2, ABCB1 and PPP1R9A expression on chromosome 7 is implicated in the pathogenesis of hepatosplenic T-cell lymphoma distinguishing it from other malignancies. PMID: 25057852
    3. Studies suggest that any change in substrate specificity of the spinophilin : PP1 holoenzyme complex was probably due to direct modification of a PP1 substrate binding surface. PMID: 22284538
    4. PPP1R9A gene is imprinted, with preferential expression from the maternal allele in embryonic skeletal muscle and extra-embryonic tissues, but biallelic expression in other embryonic tissues. PMID: 15286155
  • 亚细胞定位：
    Cytoplasm, cytoskeleton. Cell junction, synapse, synaptosome.
  • 数据库链接：

    HGNC: 14946

    OMIM: 602468

    KEGG: hsa:55607

    STRING: 9606.ENSP00000405514

    UniGene: Hs.21816