PPP2R3B Antibody
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货号:CSB-PA008893
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规格:¥880
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其他:
产品详情
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Uniprot No.:Q9Y5P8
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基因名:
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别名:NY REN 8 antibody; NY REN 8 antigen antibody; P2R3B_HUMAN antibody; PP2A B'' subunit PR48 antibody; PP2A subunit B isoform PR48 antibody; PP2A subunit B PR48 isoform antibody; PPP2R3B antibody; PPP2R3L antibody; PPP2R3LY antibody; PR 48 antibody; PR48 antibody; Protein phosphatase 2 (formerly 2A) regulatory subunit B'' beta antibody; Protein phosphatase 2 regulatory subunit B'' beta antibody; Protein phosphatase 2A 48 kDa regulatory subunit antibody; Serine/threonine protein phosphatase 2A 48kDa regulatory subunit B antibody; Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta antibody
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宿主:Rabbit
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反应种属:Human
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免疫原:Synthesized peptide derived from the Internal region of Human PR48.
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免疫原种属:Homo sapiens (Human)
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标记方式:Non-conjugated
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抗体亚型:IgG
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纯化方式:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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产品提供形式:Liquid
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应用范围:WB, ELISA
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推荐稀释比:
Application Recommended Dilution WB 1:500-1:2000 ELISA 1:10000 -
Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
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基因功能参考文献:
- PPP2R3B codes for the PR70 protein, a regulatory substrate-recognizing subunit of protein phosphatase 2A. PR70 decreased melanoma growth by negatively interfering with DNA replication and cell cycle progression through its role in stabilizing CDC6-chromatin licensing and CDT1 interaction PMID: 27974665
- Results show the crystal structure of PR48/PR70, at 2.0 A degrees resolution with two domain elongated structure and two Ca2+ binding EF-hands Scattering data. PMID: 25007185
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亚细胞定位:Nucleus.
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数据库链接:
HGNC: 13417
OMIM: 300339
KEGG: hsa:28227
STRING: 9606.ENSP00000375080
UniGene: Hs.124942
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