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PPP2R3C Antibody

  • 货号：
    CSB-PA003843
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of HuvEc cells using PPP2R3C Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q969Q6
  • 基因名：
  • 别名：
    C14orf10 antibody; Chromosome 14 open reading frame 10 antibody; G4-1 antibody; G5pr antibody; Hypothetical protein FLJ20644 antibody; P2R3C_HUMAN antibody; ppp2r3c antibody; protein phosphatase 2 (formerly 2A), regulatory subunit B'', gamma antibody; Protein phosphatase 2 regulatory subunit B''gamma antibody; protein phosphatase 2, regulatory subunit B'', gamma antibody; Protein phosphatase subunit G5PR antibody; rhabdomyosarcoma antigen MU-RMS-40.6A antibody; Rhabdomyosarcoma antigen MU-RMS-40.6A/6C antibody; rhabdomyosarcoma antigen Mu-RMS-40.6C antibody; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human PPP2R3C.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May regulate MCM3AP phosphorylation through phosphatase recruitment. May act as a negative regulator of ABCB1 expression and function through the dephosphorylation of ABCB1 by TFPI2/PPP2R3C complex. May play a role in the activation-induced cell death of B-cells.
  • 基因功能参考文献：
    1. Knockdown of PP5 and/or PPP2R3C increased P-gp expression and lowered the sensitivity to vincristine and doxorubicin. Consequently, results indicate that PP5/PPP2R3C negatively regulates P-gp expression and function. PMID: 24333728
    2. G5PR expression is markedly augmented in the centrocytes of germinal centers after immunization of transgenic mice with T cell-dependent antigen. PMID: 22753944
  • 亚细胞定位：
    Nucleus. Cytoplasm.
  • 组织特异性：
    Ubiquitously expressed in brain and other tissues.
  • 数据库链接：

    HGNC: 17485

    OMIM: 615902

    KEGG: hsa:55012

    STRING: 9606.ENSP00000261475

    UniGene: Hs.530712