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PRKAR1B Antibody

  • 货号：
    CSB-PA018696ESR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: PRKAR1B antibody at 2.66μg/ml
      Lane 1: HepG2 whole cell lysate
      Lane 2: Jurkat whole cell lysate
      Lane 3: 293T whole cell lysate
      Lane 4: Hela whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 43 kDa
      Observed band size: 43 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PRKAR1B Polyclonal antibody
  • Uniprot No.：
    P31321
  • 基因名：
  • 别名：
    cAMP dependent protein kinase type I beta regulatory subunit antibody; cAMP-dependent protein kinase type I-beta regulatory subunit antibody; KAP1_HUMAN antibody; PKARI beta antibody; PRKAR 1 antibody; PRKAR 1B antibody; PRKAR1 antibody; Prkar1b antibody; PRKAR1B protein antibody; Protein kinase cAMP dependent regulatory type I beta antibody; RIbeta antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human cAMP-dependent protein kinase type I-beta regulatory subunit protein (190-290AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.
  • 基因功能参考文献：
    1. No pathogenic PRKAR1B mutations were found in early onset familial dementia patients in a Dutch cohort. PMID: 25108559
    2. This study demonistrated that PRKAR1B mutation associated with a new neurodegenerative disorder with unique pathology. PMID: 24722252
    3. The paired-like homeodomain protein, Arix, mediates protein kinase A-stimulated dopamine beta-hydroxylase gene transcription through its phosphorylation status PMID: 11943777
  • 亚细胞定位：
    Cell membrane.
  • 蛋白家族：
    CAMP-dependent kinase regulatory chain family
  • 组织特异性：
    Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.
  • 数据库链接：

    HGNC: 9390

    OMIM: 176911

    KEGG: hsa:5575

    STRING: 9606.ENSP00000353415

    UniGene: Hs.520851