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PSG9 Antibody

  • 货号：
    CSB-PA27499A0Rb
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • IHC image of CSB-PA27499A0Rb diluted at 1:100 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA27499A0Rb diluted at 1:100 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of MCF-7 cells with CSB-PA27499A0Rb at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PSG9 Polyclonal antibody
  • Uniprot No.：
    Q00887
  • 基因名：
    PSG9
  • 别名：
    pregnancy specific beta 1 glycoprotein (PSG) antibody; pregnancy specific beta 1 glycoprotein 11 antibody; pregnancy specific beta 1 glycoprotein 9 antibody; pregnancy specific beta 1 glycoprotein B antibody; Pregnancy-specific beta-1 glycoprotein B antibody; Pregnancy-specific beta-1-glycoprotein 11 antibody; Pregnancy-specific beta-1-glycoprotein 9 antibody; Pregnancy-specific glycoprotein 11 antibody; Pregnancy-specific glycoprotein 7 antibody; Pregnancy-specific glycoprotein 9 antibody; PS beta B antibody; PS-beta-B antibody; PS-beta-G-11 antibody; PS-beta-G-9 antibody; PS34 antibody; PSBG 9 antibody; PSBG-11 antibody; PSBG-9 antibody; PSG 9 antibody; PSG11 antibody; PSG7 antibody; PSG9 antibody; PSG9_HUMAN antibody; PSGII antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Pregnancy-specific beta-1-glycoprotein 9 protein (241-426AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，PSG9 Antibody (CSB-PA27499A0Rb)，的标记方式是Non-conjugated。对于PSG9 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA27499B0Rb PSG9 Antibody, HRP conjugated ELISA
    FITC CSB-PA27499C0Rb PSG9 Antibody, FITC conjugated
    Biotin CSB-PA27499D0Rb PSG9 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. Results indicate that pregnancy-specific glycoprotein 9 (PSG9) may facilitate the development of hepatocellular carcinoma (HCC) by fostering angiogenesis via promoting VEGFA production in cancer HCC. PMID: 28078509
    2. Findings illustrate the innovative mechanism by which PSG9 drives the progression of colorectal cancer and tumor angiogenesis. This occurs via nuclear translocation of PSG9/SMAD4, which activates angiogenic cytokines. PMID: 27528036
    3. PSG9, through its activation of TGFbeta-1, could be a potent inducer of immune tolerance PMID: 27389696
    4. PSG9 may have a role in development of colorectal carcinogenesis in patients with adenomatous polyposis coli PMID: 15982419
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Immunoglobulin superfamily, CEA family
  • 数据库链接：

    HGNC: 9526

    OMIM: 176398

    KEGG: hsa:5678

    STRING: 9606.ENSP00000270077

    UniGene: Hs.502092