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PSMD12 Antibody

  • 货号：
    CSB-PA003868
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of HepG2 cells using PSMD12 Polyclonal Antibody
    • Western Blot analysis of various cells using PSMD12 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    O00232
  • 基因名：
    PSMD12
  • 别名：
    26S proteasome non-ATPase regulatory subunit 12 antibody; 26S proteasome regulatory subunit p55 antibody; 26S proteasome regulatory subunit RPN5 antibody; MGC75406 antibody; p55 antibody; proteasome (prosome, macropain) 26S subunit, non ATPase12 antibody; Proteasome 26S non ATPase subunit 12 isoform 2 antibody; PSD12_HUMAN antibody; PSMD12 antibody; Rpn5 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human PSMD12.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
  • 基因功能参考文献：
    1. we identified six de novo genomic deletions and four de novo point mutations in unrelated individuals with intellectual disability, congenital malformations, ophthalmologic anomalies, feeding difficulties, deafness, and subtle dysmorphic facial features PMID: 28132691
  • 相关疾病：
    Stankiewicz-Isidor syndrome (STISS)
  • 蛋白家族：
    Proteasome subunit p55 family
  • 数据库链接：

    HGNC: 9557

    OMIM: 604450

    KEGG: hsa:5718

    STRING: 9606.ENSP00000348442

    UniGene: Hs.4295