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PSMD6 Antibody

  • 货号：
    CSB-PA614875PA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Jurkat whole cell lysate, K562 whole cell lysate
      All lanes: PSMD6 antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 46, 42, 52 kDa
      Observed band size: 46 kDa
    • IHC image of CSB-PA614875PA01HU diluted at 1:100 and staining in paraffin-embedded human prostate tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of MCF-7 cells with CSB-PA614875PA01HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PSMD6 Polyclonal antibody
  • Uniprot No.：
    Q15008
  • 基因名：
    PSMD6
  • 别名：
    26S proteasome non-ATPase regulatory subunit 6 antibody; 26S proteasome regulatory subunit RPN7 antibody; 26S proteasome regulatory subunit S10 antibody; Breast cancer-associated protein SGA-113M antibody; KIAA0107 antibody; p42A antibody; P44S10 antibody; PFAAP4 antibody; Phosphonoformate immuno-associated protein 4 antibody; Proteasome (prosome; macropain) 26S subunit; non-ATPase; 6 antibody; Proteasome regulatory particle subunit p44S10 antibody; PSMD6 antibody; PSMD6_HUMAN antibody; Rpn7 antibody; S10 antibody; SGA-113M antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Peptide sequence from Human 26S proteasome non-ATPase regulatory subunit 6 protein (355-372AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，PSMD6 Antibody (CSB-PA614875PA01HU)，的标记方式是Non-conjugated。对于PSMD6 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA614875PB01HU PSMD6 Antibody, HRP conjugated ELISA
    FITC CSB-PA614875PC01HU PSMD6 Antibody, FITC conjugated
    Biotin CSB-PA614875PD01HU PSMD6 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
  • 基因功能参考文献：
    1. Suggest AK124742 and PSMD6 as a new lncRNA-messenger RNA gene pair in human cumulus cells that may be considered as potential biomarkers to aid embryo selection. PMID: 25670720
    2. we observed that the PSMD6 variant rs831571 might be associated with the therapeutic efficacy of rosiglitazone and repaglinide in Chinese patients with type 2 diabetes. PMID: 26024304
    3. interaction of Rpn7 with DNA damage response foci in situ mediates the protection of DNA damage foci from premature resolution. PMID: 22473755
  • 蛋白家族：
    Proteasome subunit S10 family
  • 数据库链接：

    HGNC: 9564

    OMIM: 617857

    KEGG: hsa:9861

    STRING: 9606.ENSP00000295901

    UniGene: Hs.152536