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  4. PTGFRN Antibody

PTGFRN Antibody

  • 货号：
    CSB-PA006299
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of 293 cells using CD315 Polyclonal Antibody
    • Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:200
  • 其他：

产品详情

  • Uniprot No.：
    Q9P2B2
  • 基因名：
    PTGFRN
  • 别名：
    CD315 antibody; CD9 partner 1 antibody; CD9P-1 antibody; CD9P1 antibody; EWI F antibody; EWI-F antibody; FLJ11001 antibody; FPRP antibody; FPRP_HUMAN antibody; Glu Trp Ile EWI motif containing protein F antibody; Glu-Trp-Ile EWI motif-containing protein F antibody; KIAA1436 antibody; Prostaglandin F2 alpha receptor associated protein antibody; Prostaglandin F2 alpha receptor regulatory protein antibody; Prostaglandin F2 receptor inhibitor antibody; Prostaglandin F2 receptor negative regulator antibody; Prostaglandin F2-alpha receptor regulatory protein antibody; Prostaglandin F2-alpha receptor-associated protein antibody; Ptgfrn antibody; SMAP 6 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human CD315.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur. In myoblasts, associates with tetraspanins CD9 and CD81 to prevent myotube fusion during muscle regeneration.
  • 基因功能参考文献：
    1. These findings show for the first time that CD9P-1 expression positively correlates with the metastatic status of human lung tumor PMID: 21206492
    2. EWI proteins EWI-2 and EWI-F, alpha3beta1 and alpha6beta4 integrins, and protein palmitoylation have contrasting effects on cell surface CD9 organization PMID: 16537545
    3. EWI-2 and EWI-F link the tetraspanin web to the actin cytoskeleton through their direct association with ezrin-radixin-moesin proteins PMID: 16690612
    4. transferrin receptor and CD9, CD81, and CD9P-1 are differentially sorted into exosomes after TPA treatment of K562 cells PMID: 17407154
    5. CD9P-1 was shown to exhibit more than 40 different N-glycans, essentially composed of complex and high mannose-type structures. PMID: 17960739
    6. Tetraspanins can play a role on CD9P-1 oligomerization status. PMID: 19703604

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  • 亚细胞定位：
    Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein.
  • 数据库链接：

    HGNC: 9601

    OMIM: 601204

    KEGG: hsa:5738

    STRING: 9606.ENSP00000376899

    UniGene: Hs.418093