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PVRIG Antibody

  • 货号：
    CSB-PA721905LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Hela whole cell lysate
      All lanes: PVRIG antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 35 kDa
      Observed band size: 35 kDa
    • Immunofluorescent analysis of A549 cells using CSB-PA721905LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
    • Western Blot
      Positive WB detected in: JK whole cell lysate
      All lanes: PVRIG antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 35 kDa
      Observed band size: 35 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PVRIG Polyclonal antibody
  • Uniprot No.：
    Q6DKI7
  • 基因名：
  • 别名：
    PVRIG; C7orf15; Transmembrane protein PVRIG; CD112 receptor; CD112R; Poliovirus receptor-related immunoglobulin domain-containing protein
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Transmembrane protein PVRIG protein (193-326AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，PVRIG Antibody (CSB-PA721905LA01HU)，的标记方式是Non-conjugated。对于PVRIG Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA721905LB01HU PVRIG Antibody, HRP conjugated ELISA
    FITC CSB-PA721905LC01HU PVRIG Antibody, FITC conjugated
    Biotin CSB-PA721905LD01HU PVRIG Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.
  • 基因功能参考文献：
    1. Blockade of TIGIT or CD112R, separately or together, enhances trastuzumab-triggered antitumor response by human NK cells. PMID: 28623459
    2. Describe CD112R, a member of poliovirus receptor-like proteins, as a new coinhibitory receptor for T cells. CD112R is preferentially expressed on T cells and inhibits T cell receptor-mediated signals. PMID: 26755705
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 组织特异性：
    Expressed in some types of immune cells. Expressed at low levels on the surface of freshly isolated T-cells and natural killer (NK) cells, predominantly on CD8+ T-cells (mainly memory/effector, but not naive cells) and on both CD16+ and CD16- NK cells. T-
  • 数据库链接：

    HGNC: 32190

    OMIM: 617012

    KEGG: hsa:79037

    STRING: 9606.ENSP00000316675

    UniGene: Hs.729356