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Phospho-NACA (S43) Antibody

  • 货号：
    CSB-PA020020
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q13765
  • 基因名：
    NACA
  • 别名：
    Alpha NAC antibody; Alpha-NAC antibody; Hom s 2.02 antibody; HSD48 antibody; MGC117224 antibody; NAC-alpha antibody; naca antibody; NACA/1.9.2 antibody; NACA_HUMAN antibody; NACA1 antibody; Nascent polypeptide associated complex alpha polypeptide antibody; Nascent polypeptide associated complex alpha subunit antibody; Nascent polypeptide associated complex subunit alpha antibody; Nascent polypeptide-associated complex subunit alpha antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from Human NACA around the phosphorylation site of S43.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites). May act as a specific coactivator for JUN, binding to DNA and stabilizing the interaction of JUN homodimers with target gene promoters.
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    NAC-alpha family
  • 组织特异性：
    Ubiquitously expressed.
  • 数据库链接：

    HGNC: 7629

    OMIM: 601234

    KEGG: hsa:4666

    UniGene: Hs.505735