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RAB6B Antibody

  • 货号：
    CSB-PA873642LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: RAB6B antibody at 5μg/ml
      Lane 1: Mouse brain tissue
      Lane 2: U251 whole cell lysate
      Lane 3: MCF-7 whole cell lysate
      Lane 4: A549 whole cell lysate
      Lane 5: K562 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 24, 23 kDa
      Observed band size: 24 kDa
    • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA873642LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA873642LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) RAB6B Polyclonal antibody
  • Uniprot No.：
    Q9NRW1
  • 基因名：
    RAB6B
  • 别名：
    9630015C03 antibody; AI844641 antibody; C330006L04Rik antibody; D9Bwg0185e antibody; OTTHUMP00000216372 antibody; RAB6B antibody; RAB6B member RAS oncogene family antibody; RAB6B_HUMAN antibody; Ras related protein Rab 6B antibody; Ras-related protein Rab-6B antibody; Small GTP binding protein antibody; Small GTPase RAB6B antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Ras-related protein Rab-6B protein (2-208AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，RAB6B Antibody (CSB-PA873642LA01HU)，的标记方式是Non-conjugated。对于RAB6B Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA873642LB01HU RAB6B Antibody, HRP conjugated ELISA
    FITC CSB-PA873642LC01HU RAB6B Antibody, FITC conjugated
    Biotin CSB-PA873642LD01HU RAB6B Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells.
  • 基因功能参考文献：
    1. Conformational changes in human neuronal Rab6B between its inactive GDP and active GTP-like state are observed mainly in the switch I and switch II regions, confirming their role as a molecular switch. PMID: 16790928
    2. The brain-specific Rab6B via Bicaudal-D1 is linked to the dynein/dynactin complex, suggesting a regulatory role for Rab6B in the retrograde transport of cargo in neuronal cells. PMID: 17707369
    3. DYNLRB1 specifically interacts with all three Rab6 isoforms and co-localises at the Golgi. PMID: 18044744
  • 亚细胞定位：
    Golgi apparatus membrane; Lipid-anchor. Endoplasmic reticulum-Golgi intermediate compartment. Cytoplasmic vesicle.
  • 蛋白家族：
    Small GTPase superfamily, Rab family
  • 组织特异性：
    Predominantly expressed in brain.
  • 数据库链接：

    HGNC: 14902

    OMIM: 615852

    KEGG: hsa:51560

    STRING: 9606.ENSP00000285208

    UniGene: Hs.715344