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RABEP2 Antibody

  • 货号：
    CSB-PA003903
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of HuvEc cells using Rabaptin-5β Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q9H5N1
  • 基因名：
    RABEP2
  • 别名：
    FLJ23282 antibody; FRA antibody; Rab GTPase binding effector protein 2 antibody; Rab GTPase-binding effector protein 2 antibody; Rabaptin 5 beta antibody; Rabaptin RAB GTPase binding effector protein 2 antibody; Rabaptin-5beta antibody; RABE2_HUMAN antibody; RABEP 2 antibody; RABEP2 antibody; RABPT5B antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Rabaptin-5β.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a role in membrane trafficking and in homotypic early endosome fusion. Participates in arteriogenesis by regulating vascular endothelial growth factor receptor 2/VEGFR2 cell surface expression and endosomal trafficking. By interacting with SDCCAG8, localizes to centrosomes and plays a critical role in ciliogenesis.
  • 基因功能参考文献：
    1. Pyk2 regulation is associated with increased expression of Fra-1 and JunD, activator protein-1 transcription factors known to be required for involucrin expression. PMID: 17205062
    2. FRA-1 expression, including its intracellular localization, may be considered a useful marker for hyperplastic and neoplastic proliferative breast disorders PMID: 17254320
  • 亚细胞定位：
    Cytoplasm. Early endosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body.
  • 蛋白家族：
    Rabaptin family
  • 数据库链接：

    HGNC: 24817

    OMIM: 611869

    KEGG: hsa:79874

    STRING: 9606.ENSP00000350934

    UniGene: Hs.555978