Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. RASA2 Antibody

RASA2 Antibody

  • 货号：
    CSB-PA622992LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescence staining of U251 cells with CSB-PA622992LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) RASA2 Polyclonal antibody
  • Uniprot No.：
    Q15283
  • 基因名：
  • 别名：
    GAP1m antibody; GTPase activating protein of RAS antibody; Ras GTPase activating protein 2 antibody; Ras GTPase-activating protein 2 antibody; RAS p21 protein activator 2 antibody; Rasa2 antibody; RASA2_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Ras GTPase-activating protein 2 protein (609-850AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，RASA2 Antibody (CSB-PA622992LA01HU)，的标记方式是Non-conjugated。对于RASA2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA622992LB01HU RASA2 Antibody, HRP conjugated ELISA
    FITC CSB-PA622992LC01HU RASA2 Antibody, FITC conjugated
    Biotin CSB-PA622992LD01HU RASA2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4).
  • 基因功能参考文献：
    1. Recurrent inactivating RASA2 mutations are associated with melanoma. PMID: 26502337
    2. GAP1m is a Ras GAP that switches off Ras signalling. GAP1m undergoes a plasma membrane association following growth factor stimulation of PI 3-kinase as a result of its PH domain binding to phosphatidylinositol 3,4,5-trisphosphate. PMID: 10074452
  • 亚细胞定位：
    Cytoplasm. Cytoplasm, perinuclear region.
  • 数据库链接：

    HGNC: 9872

    OMIM: 601589

    KEGG: hsa:5922

    STRING: 9606.ENSP00000286364

    UniGene: Hs.655941