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RASL10A Antibody

  • 货号：
    CSB-PA006673
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of MOUSE-SPLEEN cells using RRP22 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q92737
  • 基因名：
    RASL10A
  • 别名：
    RASL10A antibody; RRP22 antibody; Ras-like protein family member 10A antibody; Ras-like protein RRP22 antibody; Ras-related protein on chromosome 22 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human RRP22.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Potent inhibitor of cellular proliferation.
  • 基因功能参考文献：
    1. RRP22 is a special neural tumor suppressor for human astrocytomas PMID: 21264544
    2. Both 5'-CpG island hypermethylation and histone modifications contribute to the frequent and prognostically unfavorable transcriptional downregulation of RRP22 in malignant gliomas. PMID: 21631628
    3. chromosome 22 have specific motor deficits in axial stability and graphomotor skills. PMID: 20646714
    4. RRP22 localizes to the nucleolus in a GTP-dependent manner and can serve as a potential tumor suppressor. PMID: 15833841
  • 亚细胞定位：
    Cell membrane; Lipid-anchor; Cytoplasmic side. Nucleus, nucleolus. Note=May cycle in and out of the nucleolus in a GTP-dependent manner.
  • 蛋白家族：
    Small GTPase superfamily, Ras family
  • 组织特异性：
    Expression appears to be strictly limited to the central nervous system.
  • 数据库链接：

    HGNC: 16954

    OMIM: 602220

    KEGG: hsa:10633

    STRING: 9606.ENSP00000216101

    UniGene: Hs.73088