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REG3G Antibody

  • 货号：
    CSB-PA751009EA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) REG3G Polyclonal antibody
  • Uniprot No.：
    Q6UW15
  • 基因名：
    REG3G
  • 别名：
    LPPM429 antibody; Pancreatitis-associated protein 1B antibody; Pancreatitis-associated protein IB antibody; PAP IB antibody; PAP-1B antibody; PAP1B antibody; PAPIB antibody; REG III antibody; Reg III-gamma antibody; REG-3-gamma antibody; REG3G antibody; REG3G_HUMAN antibody; Regenerating islet derived 3 gamma antibody; Regenerating islet-derived protein 3-gamma antibody; Regenerating islet-derived protein III-gamma antibody; UNQ429 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Regenerating islet-derived protein 3-gamma protein (27-175AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，REG3G Antibody (CSB-PA751009EA01HU)，的标记方式是Non-conjugated。对于REG3G Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA751009EB01HU REG3G Antibody, HRP conjugated ELISA
    FITC CSB-PA751009EC01HU REG3G Antibody, FITC conjugated
    Biotin CSB-PA751009ED01HU REG3G Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and differentiation after skin injury.
  • 基因功能参考文献：
    1. This gene encodes a secreted peptide that displays antimicrobial activity against Gram-positive bacteria. PMID: 16931762
    2. a model of CagA-directed REG3gamma expression in gastric epithelial cells via activation of the IL-11/gp130/STAT3 pathway PMID: 22312430
    3. REG III was identified and expressed predominantly in pancreas and testis, but not in small intestine PMID: 15556304
    4. PAP IB represents a good example of duplication and divergence, probably with the acquisition of new functions, thus participating in the evolution of the protein repertoire. PMID: 15777617
  • 亚细胞定位：
    Secreted. Cytoplasm.
  • 组织特异性：
    Predominantly expressed in pancreas, where it may be restricted to exocrine pancreas. Moderate expression levels in testis and weak in heart, kidney and placenta.
  • 数据库链接：

    HGNC: 29595

    OMIM: 609933

    KEGG: hsa:130120

    STRING: 9606.ENSP00000272324

    UniGene: Hs.447084