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RELT Antibody

  • 货号：
    CSB-PA08179A0Rb
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescence staining of PC-3 cells with CSB-PA08179A0Rb at 1:40, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
    • Western blot
      All lanes: RELT antibody at 2µg/ml + 293T whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 47 kDa
      Observed band size: 47 kDa
    • Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA08179A0Rb at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) RELT Polyclonal antibody
  • Uniprot No.：
    Q969Z4
  • 基因名：
    RELT
  • 别名：
    Receptor expressed in lymphoid tissues antibody; Relt antibody; TNFRSF19L antibody; TR19L_HUMAN antibody; Tumor necrosis factor receptor superfamily member 19L antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Tumor necrosis factor receptor superfamily member 19L protein (26-153AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，RELT Antibody (CSB-PA08179A0Rb)，的标记方式是Non-conjugated。对于RELT Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA08179B0Rb RELT Antibody, HRP conjugated ELISA
    FITC CSB-PA08179C0Rb RELT Antibody, FITC conjugated
    Biotin CSB-PA08179D0Rb RELT Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
    IF 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May play a role in apoptosis. Induces activation of MAPK14/p38 and MAPK8/JNK MAPK cascades, when overexpressed. Involved in dental enamel formation.
  • 基因功能参考文献：
    1. Collectively, this study provides more insights into RELT expression, RELT family member function, and the mechanism of RELT-induced death. PMID: 28688764
    2. report that overexpression of RELT or its homologues RELL1 and RELL2 in HEK 293 epithelial cells results in cell death with morphological characteristics consistent with the activation of an apoptotic pathway. PMID: 19969290
    3. Receptor expressed in lymphoid tissue (RELT) and its novel homologues RELL1 and RELL2 co-localize with one another at the plasma membrane. PMID: 16389068
  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein. Cytoplasm. Cytoplasm, perinuclear region.
  • 蛋白家族：
    RELT family
  • 组织特异性：
    Spleen, lymph node, brain, breast and peripheral blood leukocytes (at protein level). Expressed highly in bone marrow and fetal liver. Very low levels in skeletal muscle, testis and colon. Not detected in kidney and pancreas.
  • 数据库链接：

    HGNC: 13764

    OMIM: 611211

    KEGG: hsa:84957

    STRING: 9606.ENSP00000064780

    UniGene: Hs.533720