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RERG Antibody

  • 货号：
    CSB-PA070062
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q96A58
  • 基因名：
    RERG
  • 别名：
    MGC15754 antibody; RAS like estrogen regulated growth inhibitor antibody; Ras related and estrogen regulated growth inhibitor antibody; Ras-related and estrogen-regulated growth inhibitor antibody; Rerg antibody; RERG_HUMAN antibody; Weakly similar to N ras protein [H.sapiens] antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human RERG.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential.
  • 基因功能参考文献：
    1. this study shows that miR-382-5p expression is negatively correlated with RERG expression, and functions as an independent oncomiR for the higher incidence and poorer prognosis of breast cancer PMID: 27705918
    2. Estradiol estrogen receptor-beta and PGE2 integrate at RERG, leading to increased endometriotic cell proliferation. PMID: 24992181
    3. Results describe the mRNA expression of CRABP1, RERG, and GRP in pituitary adenomas. PMID: 21270509
    4. Loss of RERG expression is associated with breast cancer and distant metastasis. PMID: 20697807
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Small GTPase superfamily, Ras family
  • 组织特异性：
    Detected in heart, brain, placenta, lung, liver, skin, kidney and pancreas. Detected in estrogen receptor-positive breast-derived cell lines, but not in estrogen receptor-negative cell lines. Expression is decreased or lost in a significant proportion of
  • 数据库链接：

    HGNC: 15980

    OMIM: 612664

    KEGG: hsa:85004

    STRING: 9606.ENSP00000256953

    UniGene: Hs.199487