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RFPL3 Antibody

  • 货号：
    CSB-PA019600LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: RFPL3 antibody at 8µg/ml
      Lane 1: Human placenta tissue
      Lane 2: HL60 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 36, 33 kDa
      Observed band size: 36 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) RFPL3 Polyclonal antibody
  • Uniprot No.：
    O75679
  • 基因名：
    RFPL3
  • 别名：
    RFPL3 antibody; Ret finger protein-like 3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Ret finger protein-like 3 protein (8-288AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，RFPL3 Antibody (CSB-PA019600LA01HU)，的标记方式是Non-conjugated。对于RFPL3 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA019600LB01HU RFPL3 Antibody, HRP conjugated ELISA
    FITC CSB-PA019600LC01HU RFPL3 Antibody, FITC conjugated
    Biotin CSB-PA019600LD01HU RFPL3 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    (Microbial infection) Stimulates the activity of Human Immunodeficiency Virus 1/HIV-1 pre-integration complex.
  • 基因功能参考文献：
    1. EGF significantly upregulated RFPL3 and hTERT protein levels in the nonsmall cell lung cancer cells. RFPL3 and hTERT proteins upregulation by EGF were attenuated by pretreatment with AG1478 and erlotinib. EGF promoted proliferation and inhibited apoptosis; PD98059 decreased RFPL3 and hTERT protein expression; and RFPL3 overexpression increased the expression of hTERT and related MEKpathway proteins PMID: 29749533
    2. RFPL3 and CBP have roles in upregulating hTERT activity and promoting lung cancer growth PMID: 26318425
    3. These results demonstrate that RFPL3 is an important cellular factor which promotes lung cancer growth by activating hTERT expression PMID: 25481043
    4. RFPL3 is a potential stimulator of human immunodeficiency virus, type 1 (HIV-1) preintegration complex integration. PMID: 25107902
    5. the human RFPL1,2,3 genes have a role in neocortex development PMID: 18656177

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  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 组织特异性：
    Expressed during neurogenesis in differentiating human embryonic stem cells and in the developing human neocortex.
  • 数据库链接：

    HGNC: 9980

    OMIM: 605970

    KEGG: hsa:10738

    STRING: 9606.ENSP00000249007

    UniGene: Hs.558455