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RNASEH2C Antibody

  • 货号：
    CSB-PA019807GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q8TDP1
  • 基因名：
    RNASEH2C
  • 别名：
    RNASEH2C antibody; AYP1 antibody; Ribonuclease H2 subunit C antibody; RNase H2 subunit C antibody; Aicardi-Goutieres syndrome 3 protein antibody; AGS3 antibody; RNase H1 small subunit antibody; Ribonuclease HI subunit C antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Human RNASEH2C
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
  • 基因功能参考文献：
    1. This study reviewed that Neurologic Phenotypes Associated with Mutations in RNASEH2C in patients with Aicardi-Goutieres Syndrome. PMID: 27643693
    2. Examination of the effect of several Aicardi-Goutieres Syndrome-related mutations in the C subunit of RNase H2. PMID: 19015152
    3. Describes an RNASEH2C pseudogene that is located close to the SRY gene on chromosome Y. PMID: 8244390
  • 相关疾病：
    Aicardi-Goutieres syndrome 3 (AGS3)
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    RNase H2 subunit C family
  • 组织特异性：
    Widely expressed.
  • 数据库链接：

    HGNC: 24116

    OMIM: 610329

    KEGG: hsa:84153

    STRING: 9606.ENSP00000308193

    UniGene: Hs.718438