RNF26 Antibody
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货号:CSB-PA019883LA01HU
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规格:¥440
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促销:
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图片:
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Western blot
All lanes: RNF26 antibody at 6µg/ml + 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 48 kDa
Observed band size: 48 kDa -
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA019883LA01HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA019883LA01HU at dilution of 1:100
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Immunofluorescent analysis of HepG2 cells using CSB-PA019883LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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其他:
产品详情
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产品名称:Rabbit anti-Homo sapiens (Human) RNF26 Polyclonal antibody
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Uniprot No.:Q9BY78
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基因名:RNF26
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别名:RNF26; E3 ubiquitin-protein ligase RNF26; RING finger protein 26
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宿主:Rabbit
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反应种属:Human
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免疫原:Recombinant Human E3 ubiquitin-protein ligase RNF26 protein (246-433AA)
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免疫原种属:Homo sapiens (Human)
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标记方式:Non-conjugated
本页面中的产品,RNF26 Antibody (CSB-PA019883LA01HU),的标记方式是Non-conjugated。对于RNF26 Antibody,我们还提供其他标记。见下表:
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:>95%, Protein G purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
产品提供形式:Liquid
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应用范围:ELISA, WB, IHC, IF
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推荐稀释比:
Application Recommended Dilution WB 1:500-1:2000 IHC 1:20-1:200 IF 1:50-1:200 -
Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
相关产品
靶点详情
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功能:E3 ubiquitin-protein ligase that plays a key role in endosome organization by retaining vesicles in the perinuclear cloud. Acts as a platform for perinuclear positioning of the endosomal system by mediating ubiquitination of SQSTM1. Ubiquitinated SQSTM1 attracts specific vesicle-associated adapters, forming a molecular bridge that restrains cognate vesicles in the perinuclear region and organizes the endosomal pathway for efficient cargo transport. Also acts as a regulator of type I interferon production in response to viral infection by mediating the formation of 'Lys-11'-linked polyubiquitin chains on TMEM173/STING, leading to stabilize TMEM173/STING. Also required to limit type I interferon response by promoting autophagic degradation of IRF3.
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基因功能参考文献:
- Study reveals the endoplasmic reticulum (ER)-located ubiquitin ligase Ring finger protein 26 (RNF26) as the global architect of the entire endosomal system, including the trans-Golgi network. PMID: 27368102
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亚细胞定位:Endoplasmic reticulum membrane; Multi-pass membrane protein.
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组织特异性:Ubiquitous. Up-regulated in several cancer cell lines.
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数据库链接:
HGNC: 14646
OMIM: 606130
KEGG: hsa:79102
UniGene: Hs.524084
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