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RPH3AL Antibody

  • 货号：
    CSB-PA891975DSR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: RPH3AL antibody at 12μg/ml
      Lane 1: LO2 whole cell lysate
      Lane 2: K562 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 35, 32 kDa
      Observed band size: 35 kDa
    • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA891975DSR1HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) RPH3AL Polyclonal antibody
  • Uniprot No.：
    Q9UNE2
  • 基因名：
    RPH3AL
  • 别名：
    Gm1753 antibody; No C2 domains protein antibody; Noc2 antibody; Rab effector Noc2 antibody; Rabphilin 3A-like (without C2 domains) antibody; Rabphilin 3A-like antibody; Rabphilin-3A-like protein antibody; RPH3AL antibody; RPH3L_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Rab effector Noc2 protein (161-315AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells. Acts as a potential RAB3B effector protein in epithelial cells.
  • 基因功能参考文献：
    1. genetic alterations in RPH3AL are associated with aggressive behavior of breast cancers and with short survival of patients. PMID: 26070152
    2. Mutations of rabphillin-3A-like gene is associated with colorectal cancers PMID: 12375017
    3. Noc2 may function as a Rab3B effector protein in epithelial cells. PMID: 15003533
  • 亚细胞定位：
    Cytoplasm. Cytoplasmic vesicle, secretory vesicle membrane. Note=Recruited to the vesicle membrane in a GTP- and RAB3B-dependent manner in epithelial cells.
  • 组织特异性：
    Moderate to high levels of expression in thyroid, ovary, stomach, heart, pancreas, skeletal muscle, kidney and liver. Also detected in epithelial cells.
  • 数据库链接：

    HGNC: 10296

    OMIM: 604881

    KEGG: hsa:9501

    STRING: 9606.ENSP00000328977

    UniGene: Hs.651925