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RPL15 Antibody

  • 货号：
    CSB-PA234128
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA234128(RPL15 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA234128(RPL15 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    P61313
  • 基因名：
    RPL15
  • 别名：
    60S ribosomal protein L15 antibody; EC45 antibody; FLJ26304 antibody; ribosomal protein L15 antibody; RL15_HUMAN antibody; RPL10 antibody; RPL15 antibody; RPLY10 antibody; RPYL10 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human RPL15
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. Aurora kinase inhibitor danusertib negatively regulated AURKB/p70S6K/RPL15 axis with the involvement of PI3K/Akt/mTOR, AMPK, and p38 MAPK signaling pathways, leading to the induction of apoptosis and autophagy in human leukemia cells. PMID: 27612557
    2. Downregulation of RPL15 is associated with tumor progression in pancreatic ductal adenocarcinoma. PMID: 26498693
    3. These data identify RPL15 as a new gene involved in Diamond-Blackfan anemia. PMID: 23812780
    4. ISG56 interacts with ribosomal protein L15 in gastric cancer cells. PMID: 21612406
    5. RPL15 gene expression is decreased in both classic and follicular variants of papillary thyroid carcinoma. PMID: 21509594
    6. RPL15 promotes cell proliferation in gastric neoplasms PMID: 16608517

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  • 相关疾病：
    Diamond-Blackfan anemia 12 (DBA12)
  • 亚细胞定位：
    Membrane; Lipid-anchor.
  • 蛋白家族：
    Eukaryotic ribosomal protein eL15 family
  • 数据库链接：

    HGNC: 10306

    OMIM: 604174

    KEGG: hsa:6138

    STRING: 9606.ENSP00000309334

    UniGene: Hs.381219