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RPL34 Antibody

  • 货号：
    CSB-PA003987
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of HuvEc cells using Ribosomal Protein L34 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    P49207
  • 基因名：
    RPL34
  • 别名：
    60S ribosomal protein L34 antibody; L34 antibody; MGC111005 antibody; Ribosomal protein L34 antibody; RL34_HUMAN antibody; rpl34 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Ribosomal Protein L34.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, IF, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the large ribosomal subunit.
  • 基因功能参考文献：
    1. The RPL34 gene was highly expressed in OSCC, while silencing RPL34 could block cell proliferation and metastasis, but promote cell apoptosis, suggesting the RPL34 gene to be a new promising clinical target for OSCC therapy. PMID: 28697409
    2. RPL34 plays an important role in the proliferation of osteosarcoma cells. PMID: 27883047
    3. RPL34 functions as an oncogene that modulates the proliferation and metastasis of esophageal cancer cells in part through the inactivation of the PI3K/Akt signaling pathway PMID: 28109079
    4. this study shows that ribosomal protein L34 promotes the proliferation, invasion and metastasis of pancreatic cancer cells PMID: 27845896
    5. RPL34 plays a critical role in cell proliferation, cell cycle distribution and apoptosis of human malignant gastric cells. PMID: 26323242
    6. over-expressed RPL34 may promote malignant proliferation of NSCLC cells, thus playing an important role in development and progress of NSCLC PMID: 26526135

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  • 亚细胞定位：
    Cytoplasm, cytosol. Cytoplasm. Endoplasmic reticulum.
  • 蛋白家族：
    Eukaryotic ribosomal protein eL34 family
  • 数据库链接：

    HGNC: 10340

    OMIM: 616862

    KEGG: hsa:6164

    STRING: 9606.ENSP00000378160

    UniGene: Hs.438227