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RPL35A Antibody

  • 货号：
    CSB-PA020248LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human lymphoid tissue using CSB-PA020248LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA020248LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) RPL35A Polyclonal antibody
  • Uniprot No.：
    P18077
  • 基因名：
    RPL35A
  • 别名：
    60S ribosomal protein L35a antibody; Cell growth-inhibiting gene 33 protein antibody; DBA5 antibody; L35A antibody; Ribosomal Protein L35a antibody; RL35A_HUMAN antibody; RPL35A antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human 60S ribosomal protein L35a protein (1-110AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，RPL35A Antibody (CSB-PA020248LA01HU)，的标记方式是Non-conjugated。对于RPL35A Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA020248LB01HU RPL35A Antibody, HRP conjugated ELISA
    FITC CSB-PA020248LC01HU RPL35A Antibody, FITC conjugated
    Biotin CSB-PA020248LD01HU RPL35A Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Required for the proliferation and viability of hematopoietic cells. Plays a role in 60S ribosomal subunit formation. The protein was found to bind to both initiator and elongator tRNAs and consequently was assigned to the P site or P and A site.
  • 基因功能参考文献：
    1. We identified 85 overlapping deletions, of which six included the RPL35A gene and all should be had Diamond-Blackfan anemia (DBA).we sequenced the remaining RNF168 gene and examined her fibroblast culture for a DNA double strand break repair deficiency. These results were normal, indicating that the immunodeficiency is unlikely to result from a RNF168 deficiency. PMID: 28432740
    2. Studies identified deletions at known Diamond-Blackfan anemia (DBA)-related ribosomal protein gene loci in 17% (9 of 51) of patients without an identifiable mutation, including RPS19, RPS17, RPS26, and RPL35A. PMID: 22045982
    3. Inhibition of cell death by ribosomal protein L35a. PMID: 12175552
    4. analysis of 2 Diamond-Blackfan anemia (DBA) patients with chromosome 3q deletions identified RPL35A as a potential DBA gene PMID: 18535205
  • 相关疾病：
    Diamond-Blackfan anemia 5 (DBA5)
  • 蛋白家族：
    Eukaryotic ribosomal protein eL33 family
  • 数据库链接：

    HGNC: 10345

    OMIM: 180468

    KEGG: hsa:6165

    STRING: 9606.ENSP00000393393

    UniGene: Hs.529631