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  4. RPLP2 Antibody

RPLP2 Antibody

  • 货号：
    CSB-PA040245
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    P05387
  • 基因名：
    RPLP2
  • 别名：
    2700049I22Rik antibody; 60S acidic ribosomal protein P2 antibody; Acidic ribosomal phosphoprotein P2 antibody; D11S2243E antibody; LP2 antibody; MGC71408 antibody; OTTMUSP00000029428 antibody; OTTMUSP00000029429 antibody; OTTMUSP00000029430 antibody; P2 antibody; Renal carcinoma antigen NY-REN-44 antibody; Ribosomal protein P2 antibody; Ribosomal protein, large, P2 antibody; RLA2_HUMAN antibody; rplP2 antibody; RPP2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Ribosomal Protein LP2.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays an important role in the elongation step of protein synthesis.
  • 基因功能参考文献：
    1. Collectively, the present results suggest that PhoRpp21 binds the loop between P11 and P12 helices through overall positively charged clusters on the surface of the complex and serves as a scaffold for PhoRpp29 to optimize structural conformation of its N-terminal helix (alpha2) in PhoRpp21, as well as C-terminal residues in PhoRpp29, for RNase P activity. PMID: 27810361
    2. Results show that the conserved C-terminal segment of P2 from three different eukaryotic species- Human, Plasmodium falciparum and Toxoplasma gondii is intrinsically disordered. PMID: 25412900
    3. relevance of the observed cross-reactive IgE autoantibodies against P2 proteins in systemic lupus eryth remains to be elucidated PMID: 21410706
    4. the eukaryotic stalk protein P2 forms a symmetric homodimer in solution, and is structurally distinct from the bacterial counterpart L12 homodimer. PMID: 20385603
    5. Ribosomal protein P2 has been identified as a novel substrate of GRK2 in HEK-293 cells where P2 phosphorylation is increased following agonist stimulation of the beta 2-adrenergic receptor under conditions of tyrosine kinase PKC and PKA inhibition. PMID: 12379128
    6. Antisense-mediated depletion may disrupt the proteome of cancer cells. PMID: 14981896
    7. Distinct roles for CD39 and P2-purinergic signaling in both tissue remodeling and fibrogenesis with respect to human pancreatic diseases. PMID: 16920697

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  • 蛋白家族：
    Eukaryotic ribosomal protein P1/P2 family
  • 数据库链接：

    HGNC: 10377

    OMIM: 180530

    KEGG: hsa:6181

    STRING: 9606.ENSP00000322419

    UniGene: Hs.437594