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RTN4RL1 Antibody

  • 货号：
    CSB-PA803121LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA803121LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA803121LA01HU at dilution of 1:100
    • Immunofluorescent analysis of A549 cells using CSB-PA803121LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) RTN4RL1 Polyclonal antibody
  • Uniprot No.：
    Q86UN2
  • 基因名：
    RTN4RL1
  • 别名：
    DKFZp547J144 antibody; NgR 3 antibody; NgR3 antibody; NGRH 2 antibody; NGRH2 antibody; NGRL2 antibody; Nogo 66 receptor homolog 2 antibody; Nogo 66 receptor related protein 3 antibody; Nogo receptor like 2 antibody; Nogo receptor-like 2 antibody; Nogo-66 receptor homolog 2 antibody; Nogo-66 receptor-related protein 3 antibody; R4RL1_HUMAN antibody; Reticulon 4 receptor like 1 antibody; Reticulon-4 receptor-like 1 antibody; RTN4RL1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Reticulon-4 receptor-like 1 protein (201-420AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，RTN4RL1 Antibody (CSB-PA803121LA01HU)，的标记方式是Non-conjugated。对于RTN4RL1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA803121LB01HU RTN4RL1 Antibody, HRP conjugated ELISA
    FITC CSB-PA803121LC01HU RTN4RL1 Antibody, FITC conjugated
    Biotin CSB-PA803121LD01HU RTN4RL1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Cell surface receptor. Plays a functionally redundant role in postnatal brain development and in regulating axon regeneration in the adult central nervous system. Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum. Protects motoneurons against apoptosis; protection against apoptosis is probably mediated by MAG. Plays a role in inhibiting neurite outgrowth and axon regeneration via its binding to neuronal chondroitin sulfate proteoglycans. Binds heparin. Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development. Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton.
  • 基因功能参考文献：
    1. Duplication of 10q22.3-q23.3 encompassing NGR3 gene is associated with congenital heart disease, microcephaly, and mild intellectual disability PMID: 26383923
    2. predominantly expressed in the neurons of the embryonic and adult nervous systems PMID: 14664809
  • 亚细胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor. Membrane raft. Perikaryon. Cell projection.
  • 蛋白家族：
    Nogo receptor family
  • 组织特异性：
    Predominantly expressed in brain. Expressed at lower levels in kidney, lung, mammary gland, placenta, salivary gland, skeletal muscle and spleen.
  • 数据库链接：

    HGNC: 21329

    OMIM: 610461

    KEGG: hsa:146760

    STRING: 9606.ENSP00000330631

    UniGene: Hs.22917