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SBNO2 Antibody

  • 货号：
    CSB-PA896873LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescent analysis of HepG2 cells using CSB-PA896873LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SBNO2 Polyclonal antibody
  • Uniprot No.：
    Q9Y2G9
  • 基因名：
    SBNO2
  • 别名：
    SBNO2 antibody; KIAA0963Protein strawberry notch homolog 2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Protein strawberry notch homolog 2 protein (6-146AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SBNO2 Antibody (CSB-PA896873LA01HU)，的标记方式是Non-conjugated。对于SBNO2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA896873LB01HU SBNO2 Antibody, HRP conjugated ELISA
    FITC CSB-PA896873LC01HU SBNO2 Antibody, FITC conjugated
    Biotin CSB-PA896873LD01HU SBNO2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IF 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Acts as a transcriptional coregulator, that can have both coactivator and corepressor functions. Inhibits the DCSTAMP-repressive activity of TAL1, hence enhancing the access of the transcription factor MITF to the DC-STAMP promoter in osteoclast. Plays a role in bone homeostasis; required as a positive regulator in TNFSF11//RANKL-mediated osteoclast fusion via a DCSTAMP-dependent pathway. May also be required in the regulation of osteoblast differentiation. Involved in the transcriptional corepression of NF-kappaB in macrophages. Plays a role as a regulator in the proinflammatory cascade.
  • 基因功能参考文献：
    1. The SBNO2 is component of the pathways that contribute to the downstream anti-inflammatory effects of IL-10. PMID: 18025162
  • 蛋白家族：
    SBNO family
  • 组织特异性：
    Detected in macrophages. IL10 regulates expression in a STAT3-dependent way.
  • 数据库链接：

    HGNC: 29158

    OMIM: 615729

    KEGG: hsa:22904

    STRING: 9606.ENSP00000354733

    UniGene: Hs.408708