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SCAF1 Antibody

  • 中文名称：
    SCAF1多克隆抗体
  • 货号：
    CSB-PA004050
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of Jurkat cells using SCAF1 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q9H7N4
  • 基因名：
    SCAF1
  • 别名：
    SCAF1 antibody; SFRS19 antibody; SRA1 antibody; Splicing factor antibody; arginine/serine-rich 19 antibody; SR-related C-terminal domain-associated factor 1 antibody; SR-related and CTD-associated factor 1 antibody; SR-related-CTD-associated factor antibody; SCAF antibody; Serine arginine-rich pre-mRNA splicing factor SR-A1 antibody; SR-A1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human SCAF1.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May function in pre-mRNA splicing.
  • 基因功能参考文献：
    1. This is the first study that examines the expression of the novel gene SR-A1 in colon cancer progression. PMID: 15493872
    2. Study describes the discovery and cloning of fifteen novel splice variants of SCAF1 gene in cancer cells comprising a total of nine novel alternative splicing events between the annotated exons of the gene, producing seven novel SCAF1 transcripts with open-reading frames, and eight novel SCAF1 transcripts with premature termination codons that are likely long non-coding RNAs. Additionally, a novel 3' UTR was discovered. PMID: 29787824
    3. This study unveils the presence of SR-A1, CD36, and LOX-1 in aortic valves and suggests potential mechanisms by which they may contribute to the pathological angiogenesis, inflammation, calcification, and lipid accumulation in AVS. PMID: 24929820
    4. Our results suggest that SRA1 is associated with cancer progression and may possibly be characterized as a new marker of unfavorable prognosis for ovarian cancer. PMID: 16631123
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Splicing factor SR family
  • 组织特异性：
    Ubiquitous. Highly expressed in fetal brain and liver, poorly expressed in salivary gland, heart, skin and ovary. Expressed in colorectal carcinomas and ovarian cancers. Overexpressed in colorectal carcinomas as compared to normal colonic mucosa.
  • 数据库链接：

    HGNC: 30403

    OMIM: 617264

    KEGG: hsa:58506

    STRING: 9606.ENSP00000353769

    UniGene: Hs.103521