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SCARF1 Antibody

  • 货号：
    CSB-PA020769GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q14162
  • 基因名：
    SCARF1
  • 别名：
    Acetyl LDL receptor antibody; Endothelial cells scavenger receptor antibody; SCARF1 antibody; Scavenger receptor class F member 1 antibody; Scavenger receptor expressed by endothelial cells 1 antibody; Scavenger receptor expressed by endothelial cells antibody; SREC antibody; SREC-I antibody; SREC_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human SCARF1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion protein. Plays a role in the regulation of neurite-like outgrowth.
  • 基因功能参考文献：
    1. Scavenger receptor SREC-I promotes double stranded RNA-mediated TLR3 activation in human monocytes PMID: 25641411
    2. These studies in addition to our earlier findings showed SREC-I to play a primary role in chaperone-associated antigen uptake both through cross priming of MHC class I molecules and entry into the class II pathway. PMID: 25155057
    3. In several assay systems this type F-scavenger receptor, termed SREC-I, bound to cell wall techoic acid in a charge dependent manner and mediated adhesion to nasal epithelial cells in vitro. PMID: 24788600
    4. GP2 is a binding partner of the scavenger receptor expressed on endothelial cells I (SREC-I) but not of SR-AI and SR-BI. Dendritic cells express SREC-I and also bind and internalize GP2. PMID: 21190681
    5. Characterization of the gene and its regulation by a novel transcription factor, endothelial zinc protein-2 PMID: 11978792
    6. SRECI binds to SRECII and has a similar tissue distribution pattern PMID: 12154095

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  • 亚细胞定位：
    Membrane; Single-pass type I membrane protein.
  • 组织特异性：
    Endothelial cells.
  • 数据库链接：

    HGNC: 16820

    OMIM: 607873

    KEGG: hsa:8578

    STRING: 9606.ENSP00000263071

    UniGene: Hs.647430