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SCFD1 Antibody

  • 货号：
    CSB-PA004053
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of A549 cells using SCFD1 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q8WVM8
  • 基因名：
    SCFD1
  • 别名：
    C14orf163 antibody; Chromosome 14 open reading frame 163 antibody; RA410 antibody; Scfd1 antibody; SCFD1_HUMAN antibody; Sec1 family domain containing 1 antibody; Sec1 family domain-containing protein 1 antibody; SLY1 antibody; SLY1 homolog antibody; Sly1p antibody; STXBP1L2 antibody; Syntaxin binding protein 1 like 2 antibody; Syntaxin-binding protein 1-like 2 antibody; Vesicle transport related protein antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human SCFD1.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi.
  • 基因功能参考文献：
    1. Mutation in SCFD1 gene is associated with amyotrophic lateral sclerosis. PMID: 27455348
    2. Study shows that the SM protein, Sly1, interacts directly with the conserved oligomeric Golgi (COG) tethering complex; Sly1-COG interaction is mediated by the Cog4 subunit, which also interacts with Syntaxin 5 through a different binding site. PMID: 19536132
  • 亚细胞定位：
    Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein.
  • 蛋白家族：
    STXBP/unc-18/SEC1 family
  • 数据库链接：

    HGNC: 20726

    KEGG: hsa:23256

    STRING: 9606.ENSP00000390783

    UniGene: Hs.369168