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SDF4 Antibody

  • 货号：
    CSB-PA861120LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: SDF4 antibody at 6µg/ml
      Lane 1: U87 whole cell lysate
      Lane 2: Jurkat whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 42, 31, 28, 24, 16, 40 kDa
      Observed band size: 42 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SDF4 Polyclonal antibody
  • Uniprot No.：
    Q9BRK5
  • 基因名：
    SDF4
  • 别名：
    45 kDa calcium-binding protein antibody; Cab45 antibody; CAB45_HUMAN antibody; Calcium binding protein antibody; PSEC0034 antibody; SDF 4 antibody; SDF-4 antibody; SDF4 antibody; Stromal cell derived factor 4 antibody; Stromal cell-derived factor 4 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human 45 kDa calcium-binding protein (37-362AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SDF4 Antibody (CSB-PA861120LA01HU)，的标记方式是Non-conjugated。对于SDF4 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA861120LB01HU SDF4 Antibody, HRP conjugated ELISA
    FITC CSB-PA861120LC01HU SDF4 Antibody, FITC conjugated
    Biotin CSB-PA861120LD01HU SDF4 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment.; Isoform 5 may be involved in the exocytosis of zymogens by pancreatic acini.
  • 基因功能参考文献：
    1. Ca(2+)-dependent changes in Cab45 mediate sorting of specific cargo molecules at the trans-Golgi network. PMID: 27138253
    2. Data reveal that the ability of Cab45S to inhibit SERCA2b activity is crucial for its role as a modulator of cell proliferation and tumor growth. PMID: 25772237
    3. The obtained results indicate that the changes in gene expression in bone marrow progenitor cells can be involved into space flight-induced osteopenia. PMID: 25509878
    4. Cab45S, a novel regulator of GRP78/BiP, suppresses endoplasmic reticulum stress-induced IRE1 activation and apoptosis by binding to and elevating GRP78/BiP, and has a role in the inhibition of ER stress-induced apoptosis. PMID: 24810055
    5. Calcium is required for the retention of Cab45 in the Golgi membranes, where Cab45 binds secretory cargo in a calcium-dependent reaction. PMID: 23266954
    6. In a yeast two-hybrid screen the EF-hand Ca(2+)-binding protein Cab45 was identified as an interaction partner of Munc18b. PMID: 17442889
    7. SDF-2, SDF-4 and SDF-5 are expressed in mammary tissues and cells and that a reduced level of SDF-2 and SDF-4 are associated with a poor clinical outcome. PMID: 19513569

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  • 亚细胞定位：
    [Isoform 1]: Golgi apparatus lumen.; [Isoform 5]: Cytoplasm. Cell membrane. Cell projection, bleb.
  • 蛋白家族：
    CREC family
  • 组织特异性：
    Ubiquitous. Isoform 5 is expressed in pancreas.
  • 数据库链接：

    HGNC: 24188

    OMIM: 614282

    KEGG: hsa:51150

    STRING: 9606.ENSP00000353094

    UniGene: Hs.42806