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SEC16B Antibody

  • 货号：
    CSB-PA853439LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA853439LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SEC16B Polyclonal antibody
  • Uniprot No.：
    Q96JE7
  • 基因名：
    SEC16B
  • 别名：
    DKFZp686C2486 antibody; FLJ23871 antibody; FLJ25761 antibody; FLJ33652 antibody; FLJ36620 antibody; KIAA1928 antibody; Leucine zipper transcription regulator 2 antibody; LZTR 2 antibody; PGPR p117 antibody; Protein SEC16 homolog B antibody; Protein transport protein Sec16B antibody; Regucalcin gene promoter region related protein antibody; Regucalcin gene promoter region related protein p117 antibody; Regucalcin gene promoter region-related protein p117 antibody; RGPR antibody; RGPR p117 antibody; RGPR-p117 antibody; SC16B_HUMAN antibody; SEC16 homolog B (S. cerevisiae) antibody; SEC16 homolog B antibody; SEC16B antibody; SEC16S antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Protein transport protein Sec16B protein (5-304AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SEC16B Antibody (CSB-PA853439LA01HU)，的标记方式是Non-conjugated。对于SEC16B Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA853439LB01HU SEC16B Antibody, HRP conjugated ELISA
    FITC CSB-PA853439LC01HU SEC16B Antibody, FITC conjugated
    Biotin CSB-PA853439LD01HU SEC16B Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. Involved in peroxisome biogenesis. Regulates the transport of peroxisomal biogenesis factors PEX3 and PEX16 from the ER to peroxisomes.
  • 基因功能参考文献：
    1. Significant associations were identified at 3.5 years for SEC16B rs10913469 with dietary parameters PMID: 27005443
    2. describe characterization of the localization and dynamics of Sec16B relative to Sec16A, provide evidence that Sec16B is likely a minor or perhaps specialized form of Sec16, and that it is not functionally redundant with S PMID: 22355596
    3. Data show that knockdown of Sec16B but not Sec16A by RNAi affected the morphology of peroxisomes, inhibited the transport of Pex16 from the ER to peroxisomes, and suppressed expression of Pex3. PMID: 21768384
    4. Data show that SNPs in SEC16B and TMEM18 were significantly associated with obesity, and the SNPs in GNPDA2, BDNF, FAIM2 and MC4R were marginally associated with obesity in Japanese. PMID: 19851340
    5. Mammalian cells contain two distinct Sec16 homologues: a large protein Sec16L of 2154 aa and a smaller protein Sec16S of 1060 aa. PMID: 17192411

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  • 亚细胞定位：
    Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein.
  • 蛋白家族：
    SEC16 family
  • 组织特异性：
    Ubiquitous.
  • 数据库链接：

    HGNC: 30301

    OMIM: 612855

    KEGG: hsa:89866

    STRING: 9606.ENSP00000308339

    UniGene: Hs.149540